View Cart || Request a 2021 Catalog

Electron Microscopy Sciences

Technical Data Sheets

Microarraying Products References

Nitrocellulose-Coated Film Substrates:

Ajikumar PK, Ng JK, Tang YC, Lee JY, Stephanopoulos G, Too H-P. 2006. Design, fabrication and functional analysis of a new protein array based on ssDNA-based assembly. MEBCS.

Alterovitz G, Liu J, Chow J, Ramoni MF. 2006. Automation, parallelism, and robotics for proteomics. Proteomics.

Angenendt P, GlÖkler J, Sobek J, Lehrach H, Cahill DJ. 2003. Next generation of protein microarray support materials: Evaluation for protein and antibody microarray applications. Journal of Chromatography A. 1009: 97-104.

Arnaud M-C, Gazarian T, Rodriguez YP, Gazarian K, Sakanyan V. 2004. Array assessment of phage-displayed peptide mimics of Human Immunodeficiency Virus type 1 gp41immunodominant epitope: Binding to antibodies of infected individuals. Proteomics. 4: 1959-64.

Averbeck M, Beilharz S, Bauer M, Gebhardt C, Hartmann A, Hochleitner K, Kauer F, Voith U, Simon JC, Termeer C. 2006. In situ profiling and quantification of cytokines released during UVB-induced inflammation by combining dermal microdialysis and protein microarrays. Exp. Dermatol. 15: 447-54.

Aziz SA, Davies M, Pick E, Zito C, Jilaveanu L, Camp RL, Rimm DL, Kluger Y, Kluger HM. 2009. Phosphatidylinositol-3-Kinase as a Therapeutic Target in Melanoma. Clinical Cancer Research. 15(9): 3029-36.

Balboni I, Chan SM, Tenenbaum JD, Butte AJ, Utz PJ. 2006. Multiplexed protein array platforms for analysis of autoimmune diseases. Annu. Rev. Immunol. 24: 391-418.

Barres BA, Koroshetz WJ, Chun LLY, Corey DP. 1990. Ion Channel Expression by White Matter Glia: The Type-1 Astrocyte. Neuron. 5: 527-44.

Becker KF, Schott C, Hipp S, Metzger V, Porschewski P, Beck R, Nährig J, Becker I, Höfler H. 2007. Quantitative protein analysis from formalin-fixed tissues: implications for translational clinical research and nanoscale molecular diagnosis. J. Pathol. 211(3): 370-8.

Belov L, de la Vega O, dos Remedios CG, Mulligan SP, Christopherson RL. 2001. Immunophenotyping of Leukemias Using a Cluster of Differentiation Antibody Microarray. Cancer Research. 61: 4483–9.

Belov L, Huang P, Barber N, Mulligan SP, Christopherson RL. 2003. Identification of repertoires of surface antigens on leukemias using an antibody microarray. Proteomics. 3: 2147-54.

Belov L, Huang P, Chrisp JS, Mulligan SP, Christopherson RI. 2005. Screening microarrays of novel monoclonal antibodies for binding to T-, B- and myeloid leukaemia cells. J Immunological Methods 305: 10-19.

Bouwman K, Qiu J, Zhou H, Schotanus M, Mangold LA, Vogt R, Erlandson E, Trenkle J, Partin AW, Misek D, Omenn GS, Haab BB, Hanash S. 2003. Microarrays of tumor cell derived proteins uncover a distinct pattern of prostate cancer serum immunoreactivity.

Braun F, Marhuenda FB, Morin A, Guevel L, Fleury F, Takahashi M, Sakanyan V. 2006. Similarity and divergence between the RNA polymerase a subunits from thermophilic Thermotoga maritima and mesophilic Escherichia coli bacteria. Gene 380: 120-6.

Braunschweig T, Kaserer K, Chung J-Y, Bilke S, Krizman D, Knezevic V, Hewitt SM. 2007. Proteomic expression profiling of thyroid neoplasms. Proteomics Clin. 1: 264-71.

Cahill DJ. 2001. Protein and antibody arrays and their medical applications. Journal of Immunological Methods. 250: 81-91.

Calvert VS, Tang Y, Boveia V, Wulfkuhle J, Schutz-Geschwender A, Olive DM, Liotta LA, Petricoin EF. 2004. Development of Multiplexed Protein Profiling and Detection Using Near Infrared Detection of Reverse-Phase Protein Microarrays. Proteomics. 1: 81-9.

Calvert VS, Collantes R, Elariny H, Afendy A, Baranova A, Mendoza M, Goodman Z, Liotta LA, Petricoin EF, Younossi ZM. 2007. A systems biology approach to the pathogenesis of obesity-related nonalcoholic fatty liver disease using reverse phase protein microarrays for multiplexed cell signaling analysis. Hepatology. 46(1): 166-72.

Carbone R, De Marni M, Zanardi A, Vinati S, Barborini E, Fornasari L, Milani P. 2009. Characterization of cluster-assembled nanostructured titanium oxide coatings as substrates for protein arrays. Analytical Biochemistry. 394(1): 7-12.

Calvo KR, Dabir B, Kovach A, Devor C, Bandle R, Bond A, Shih JH, Jaffe ES. 2008. IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma. Blood. 112(9): 3818-26.

Chan SM, Ermann J, Su L, Fathman CG, Utz PJ. 2004. Protein microarrays for multiplex analysis of signal transduction pathways. Nat. Med. 10(12) 1390-6.

Chang Y-J, Hu C-Y, Yin L-T, Chang C-H, Su H-J. 2008. Dividable membrane with multi-reaction wells for microarray biochips. Journal of Bioscience and Bioengineering. 106(1): 59-64.

Charboneau L, Scott H, Chen T, Winters M, Petricoin EF, Liotta LA, Paweletz CP. 2002. Utility of reverse phase protein arrays: Applications to signalling pathways and human body arrays. Briefings in functional Genomics and Proteomics. 1(3): 305-15.

Chatterjee M, Mohapatra S, Ionan A, Bawa G, Ali-Fehmi R, Wang X, Nowak J, Ye B, Nahhas FA, Lu K, Witkin SS, Fishman D, Munkarah A, Morris R, Levin NK, Shirley NN, Tromp G, Abrams J, Draghici S, Tainsky MA. 2006. Diagnostic Markers of Ovarian Cancer by High-Throughput Antigen Cloning and Detection on Arrays. Cancer Research. 66: 1181-90.

Chatterjee M, Ionan A, Draghici S, Tainsky MA. 2006. Epitomics: global profiling of immune response to disease using protein microarrays. OMICS. 10(4): 499-506.

Cho WCS. 2007. Contribution of oncoproteomics to cancer biomarker discovery. Molecular Cancer. 6(25).

Christopherson RI, Stoner K, Barber N, Belov L, Woolfson A, Scott M, Bendall L, Mulligan SP. 2006. Classification of AML using a monoclonal antibody microarray. Methods Mol. Med. 125: 241-51.

Cinier M, Petit M, Williams MN, Fabre RM, Pecorari F, Talham DR, Bujoli B, Tellier C. 2009. Bisphosphonate Adaptors for Specific Protein Binding on Zirconium Phosphonate-based Microarrays. Bioconjugate Chem. 20(12): 2270-7.

Colombo JA, Napp MI, Yáñez A, Reisin H. 2001. Tissue printing of astroglial interlaminar processes from human and non-human primate cerebral cortex. Brain Research Bulletin. 55(4): 561-5.

Davies DH, Liang X, Hernandez JE, Randall A, Hirst S, Mu Y, Romero KM, Nguyen TT, Kalantari-

Dehaghi M, Crotty S, Baldi P, Villarreal LP, Felgner PL. 2005a. Profiling the humoral response to infection using proteome microarrays: High-throughput vaccine and diagnostic antigen discovery. PNAS. 102(3): 547-52.

Davies DH, McCausland MM, Valdez C, Huynh D, Hernandez JE, Mu Y, Hirst S, Villarreal L, Felgner PL, Crotty S. 2005b. Vaccinia Virus H3L Envelope Protein Is a Major Target of Neutralizing Antibodies in Humans and Elicits Protection against Lethal Challenge in Mice. Journal of Virology. 79(18): 11724-33.

Davies DH, Molina DM, Wrammert J, Miller J, Hirst S, Mu Y, Pablo J, Unal B, Nakajima-Sasaki R, Liang X, Crotty S, Karem KL, Damon IK, Ahmed R, Villarreal L, Felgner P. 2007. Proteome-wide analysis of the serological response to vaccinia and smallpox. Proteomics. 7: 1678-86.

Davuluri G, Espina V, Petricoin EF, Ross M, Deng J, Liotta LA, Glaser BM. 2009. Activated VEGF receptor shed into the vitreous in eyes with wet AMD. Archives of Ophthalmology. 127(5): 613-21.

Dinca V, Catherine J, Mourka A, Georgiou S, Farsari M, Fotakis C. 2009. 2D and 3D biotin patterning by ultrafast lasers. International ournal of Nanotechnology. 6(1-2): 88-98.

Dinca V, Farsari M, Kafetzopoulos D, Popescu A, Dinescu M, Fotakis C. 2008. Patterning parameters for biomolecules microarrays constructed with nanosecond and femtosecond UV lasers. The Solid Films. 18(31): 6504-11.

Dinca V, Ranella A, Farsari M, Kafetzopoulos D, Dinescu M, Popescu A, Fotakis C. 2008. Quantification of the activity of biomolecules in microarrays obtained by direct laser transfer. 10(5): 719-25.

Dinca V, Ranella A, Popescu A, Dinescu M, Farsari M, Fotakis C. 2007. Parameters optimization for biological molecules patterning using 248-nm ultrafast lasers. Applied Surface Science. 254(4): 1164-8.

Espejo A, Cote J, Bednarek A, Richard S, Beford MT. 2002. A protein-domain microarray identifies novel protein–protein interactions. Biochem J. 367: 697-702.

Espina V, Woodhouse EC, Wulfkuhle J, Asmussen HD, Petricoin EF, Liotta LA. 2004. Protein microarray detection strategies: focus on direct detection technologies. Journal of Immunological Methods. 290: 121-33.

Espina V, Edmiston KH, Heiby M, Pierobon M, Sciro M, Merritt B, Banks S, Deng J, VanMeter AJ, Geho DH, Pastore L, Sennesh J, Petricoin EF, Liotta LA. 2008. A portrait of tissue phosphoprotein stability in the clinical tissue procurement process. Molecular and Cellular Proteomics. 7(10): 1998-2018.

Espina V, Mueller C, Edmiston K, Sciro M, Petricoin EF, Liotta LA. 2009a. Tissue is alive: New technologies are needed to address the problems of protein biomarker pre-analytical variability. Proteomics Clin. Appl. 3: 874-82.

Espina V, Wulfkuhle J, Liotta LA. 2009b. Application of laser microdissection and reverse-phase protein microarrays to the molecular profiling of cancer signal pathway networks in the tissue microenvironment. Clin. Lab. Med. 29(1): 1-13.

Fan Y-H, Hu Z, Li C, Wang L-E, Guo Z, Qiao Y, Zhang L, Zhang W, Mao L, Wei Q. 2007. In vitro expression levels of cell-cycle checkpoint proteins are associated with cellular DNA repair capacity in peripheral blood lymphocytes: a multivariate analysis. J. Proteome Res. 6(4): 1560-7.

Feilner T, Chai W. 2004a. Oligosaccharide microarrays to decipher the glyco code. Nature Reviews Molecular Cell Biology. 5: 582-8.

Feilner T, Hultschig C, Lee J, Meyer S, Immink RGH, Koenig A, Possling A, Seitz H, Beveridge A, Scheel D, Cahill DJ, Lehrach H, Kreutzberger J, Kersten K. 2005. High Throughput Identification of Potential Arabidopsis Mitogen-activated Protein Kinases Substrates. Molecular and Cellular Proteomics.

Feilner T, Kersten B. 2007. Phosphorylation studies using plant protein microarrays. Methods Mol. Bio. 355: 379-90.

Feilner T, Kreutzberger J, Niemann B, Kramer A, Possling A, Seitz H, Kersten B. 2004b. Proteomic Studies Using Microarrays. Current Proteomics. 1(4): 283-95.

Feizi T, Fazio F, Chai W, Wong C-H. 2003. Carbohydrate microarrays — a new set of technologies at the frontiers of glycomics. Current Opinion in Structural Biology. 13: 637-45.

Fernández-Madrid F, Tang N, Alansari H, Granda JL, Tait L, Amirikia KC, Moroianu M, Wang X, Karvonen RL. 2004. Autoantibodies to Annexin XI-A and Other Autoantigens in the Diagnosis of Breast Cancer. Cancer Research. 64: 5089-96.

Fröhlich H, Sahin Ö, Arlt D, Bender C, Beißbarth T. 2009. Deterministic Effects Propagation Networks for reconstructing protein signaling networks from multiple interventions. BMC Bioinformatics. 10(322).

Fukui S, Feizi T, Galustian C, Lawson AM, Chai W. 2002. Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions. Nature Biotechnology. 20: 1011-17.

Gagné J-P, Isabelle M, Lo KS, Bourassa S, Hendzel MJ, Dawson VL, Dawson TM, Poirier GG. 2008. Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Research. 36(22): 6959-76.

Geho D, Lahar N, Gurnani P, Huebschman M, Hermann P, Espina V, Shi A, Wulfkuhle J, Garner H, Petricoin E, Liotta LA, Rosenblatt KP. 2005. Pegylated, steptavidin-conjugated quantum dots are effective detection elements for reverse-phase protein microarrays. Bioconjugate Chem. 16(3): 599-66.

Gromov P, Celis JE, Gromova I, Rank F, Timmermans-Wielenga V, Moreira JMA. 2008. A single lysis solution for the analysis of tissue samples by different proteomic technologies. Molecular Oncology. 2(4): 368-79.

Grote T, Siwak DR, Fritsche HA, Joy C, Mills GB, Simeone D, Whitcomb DC, Logsdon C. 2008. Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: Accurate detection of CA19-9 levels in pancreatic cancer. Proteomics. 8: 3051-60.

Grubb RL, Calvert VS, Wulkuhle JD, Paweletz CD, Linehan WM, Phillips JL, Chuaqui R, Valasco A,

Gillespie J, Emmert-Buck M, Liotta LA, Petricoin EF. 2003. Signal pathway profiling of prostate cancer using reverse phase protein arrays. Proteomics. 3: 2142-6.

Guilleaume B, Bune A, Schmidt C, Klimek F, Moldenhauer G, Huber W, Arlt D, Korf U, Wiemann S, Poustka A. 2005. Systematic comparison of surface coatings for protein microarrays. Proteomics. 5: 4705-12.

Gul O, Basaga H, Kutuk O. 2008. Apoptotic blocks and chemotherapy resistance: strategies to identify Bcl-2 protein signatures. Briefings in Functional Genomics. 7(1): 27-34.

Gulmann C, Espina V, Petricoin EF, Longo DL, Santi M, Knutsen T, Raffeld M, Jaffe ES, Liotta LA, Feldman AL. 2005. Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma. Clin. Cancer Res. 11(16): 5847-55.

Gupta R, Kus R, Fladd C, Wasmuth J, Tonikian R, Sidhu S, Krogan NJ, Parkinson J, Rotin D. 2007. Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Molecular Systems Biology. 3:116.

Gutjahr C, Murphy D, Lueking A, Koenig A, Janitz M, O’Brien J, Korn B, Horn S, Lehrach H, Cahill DJ. 2005. Mouse protein arrays from a TH1 cell cDNA library for antibody screening and serum profiling. Genomics. 85(3): 285-96.

Haab BB, Geierstanger BH, Michailidis G, Vitzthum F, Forrester S, Okon R, Saviranta P, Brinker A, Sorette M, Perlee L, Suresh S, Drwal G, Adkins JN, Omenn GS. 2005. Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: Systematic variation between sample types and calibration of mass spectrometry data.Proteomics. 5: 3278-91.

Hall DA, Ptacek J, Snyder M. 2007. Protein Microarray Technology. Mech. Ageing. Dev. 128(1): 161-7.
He M, Wang M-W. 2007. Arraying proteins by cell-free synthesis. Biomolecular Engineering. 24(4): 375-80.

Ho S-W, Ghil J, Chen CTL, Johnston M, Snyder M. 2006. Linking DNA-binding proteins to their recognition sequences by using protein microarrays. PNAS 103(26): 9940-5.

Horn S, Lueking A, Murphy D, Staudt A, Gutjahr C, Schulte K, König A, Landsberger M, Lehrach H, Felix SB, Cahill DJ. 2004. Profiling humoral autoimmune repertoire of dilated cardiomyopathy (DCM) patients and development of a disease-associated protein chip. Proteomics. 6(2): 605-13.

Howbrook DN, van der Valk AM, O’Shaughnessy MC, Sarker DK, Baker SC, Lloyd AW. 2003. Developments in microarray technologies. Drug Discovery Today. 8(14): 642-51.

Ivanov SS, Chung AS, Yuang Z-l, Guan Y-i, Sachs KV, Reichner JS, Chin YE. 2004. Antibodies immobilized as arrays to profile protein post-translational modifications in mammalian cells. Molecular and Cellular Proteomics. 3(8): 788-95.

Jones MB, Krutzsch H, Shu H, Zhao Y, Liotta LA, Kohn EC, Petricoin EF. 2002. Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer. Proteomics. 2: 76-84.

Jiang L, Yu Z, Du W, Tang Z, Jiang T, Zhang C, Lu Z. 2008. Development of a fluorescent and colorimetric detection methods-based protein microarray for serodiagnosis of TORCH infections. Biosensors and Bioelectronics. 24(3): 376-82.

Kersten B, Feilner T. 2007. Generation of plant protein microarrays and investigation of antigen-antibody interactions. Methods Mol. Biol. 355: 365-78.

Kersten B, Feilner T, Kramer A, Wehrmeyer S, Possling A, Witt I, Zanor MI, Stracke R, Lueking A, Kreutzberger J, Lehrach H, Cahill DJ. 2003. Generation of Arabidopsis protein chips for antibody and serum screening. Plant Molecular Biology. 52: 999-1010.

Kersten B, Possling A, Blaesing F, Mirgorodskaya E, Gobom J, Seitz H. 2004. Protein microarray technology and ultraviolet crosslinking combined with mass spectrometry for the analysis of protein-DNA interactions. Analytical Biochemistry. 331: 303-13.

Kim J, Daniel J, Espejo A, Lake A, Krishna M, Xia L, Zhang Y, Bedford MT. 2006. Tudor, MBT and chromo domains gauge the degree of lysine methylation. EMBO Reports. 7(4): 397-403.

Kim T-E, Park S-W, Cho N-Y, Choi S-Y, Yong T-S, Nahm B-H, Lee S, Noh G. 2002. Quantitative measurement of serum allergen-specific IgE on protein chip. Exp. Mol. Med. 34(2): 152-8.

Kingsmore SF. 2006. Multiplexed protein measurement: technologies and applications of protein and antibody arrays. Nat. Rev. Drug Discov. 5(4): 310-20.

Knezevic V, Leethanakul C, Bichsel VE, Worth JM, Prabhu VV, Gutkind JS, Liotta LA, Munson PJ, Petricoin EF, Krizman DB. 2001. Proteomic profiling of the cancer microenvironment by antibody arrays. Proteomics. 1271-78.

Knight PR, Sreekumar A, Siddiqui J, Laxman B, Copeland S, Chinnaiyan A, Remick DG. 2004. Development of a Sensitive Microarray Immunoassay and Comparison with standard Enzyme-Linked Immunoassay for Cytokine Analysis. Shock. 21(1): 26-30.

Kopf E, Shnitzer D, Zharhary D. 2005. Panorama Ab Microarray Cell Signaling kit: A unique tool for protein expression analysis. Proteomics. 5(9): 2412-6.

Kornblau SM, Tibes R, Qiu YH, Chen W, Kantarjian HM, Andreeff M, Coombes KR, Mills GB. 2009. Functional proteomic profiling of AML predicts response and survival. Blood. 113(1): 154-64.

Kramer A, Feilner T, Possling A, Radchuck V, Weschke W, Bürkle L, Kersten B. 2004. Identification of barley CK2a targets by using the protein microarray technology. Phytochemistry 65: 1777-84.

Kreutzberger J. 2006. Protein microarrays: a chance to study microorganisms? Appl. Microbiol. Biotechnol. 70: 383-90.

Kukar T, Eckenrode S, Gu Y, Lian W, Megginson M, She J-X, Wu D. 2002. Protein Microarrays to Detect Protein–Protein Interactions Using Red and Green Fluorescent Proteins. Analytical Biochemistry. 306(1): 50-4.

LaBaer J, Ramachandran N. 2005. Protein microarrays as tools for functional proteomics. Current Opinion in chemical Biology. 9: 14-9.

Lash GE, Scaife PJ, Innes BA, Otun HA, Robson SC, Searle RF, Bulmer JN. 2006.Comparison of three multiplex cytokine analysis systems: Luminex, SearchLight™ and FAST Quant®. J. Immunological Methods. 309(1-2): 205-9.

Li Y, Reichert WM. 2003a. Adapting cDNA microarray format to cytokine detection protein arrays. Langmuir. 19(5): 1557-66.

Li Y, Schutte RJ, Abu-Shakra A, Reichert WM. 2005. Protein array method for assessing in-vitro biomaterial-induced cytokine expression. Biomaterials. 26: 1081-5.

Li Y, Nath N, Reichert WM. 2005. Protein array method for assessing in-vitro biomaterial-induced cytokine expression. Biomaterials. 26: 108-5.

Li Q-Z, Zhou J, Wandstrat AE, Carr-Johnson F, Branch V, Karp DR, Mohan C, Wakeland EK, Olsen NJ. 2006. Protein array autoantibody profiles for insight into systemic lupus erythematosus and incomplete lupus syndrome. Clin. Exp. Immunol. 147: 60-70.

Li C, Simeone DM, Brenner DE, Anderson MA, Shedden KA, Ruffin MT, Lubman DM. 2009. Pancreatic Cancer Serum Detection Using A Lectin/Glyco-Antibody Array Method. J Proteome Res. 8(2): 483-92.

Liotta LA, Espina V, Mehta AI, Calvert V, Rosenblatt K, Geho D, Munson PJ, Young L, Wulfkuhle J, Petricoin EF. 2003. Protein microarrays: Meeting analytical challenges for clinical applications. Cancer Cell. 3: 317-25.

Liu MY, Cai S, Espejo A, Bedford MT, Walker CL. 2002. 14-3-3 Interacts with the Tumor Suppressor Tuberin at Akt Phosphorylation Site(s). Cancer Research. 62: 6475-80.

Loebke C, Sueltmann H, Schmidt C, Henjes F, Wiemann S, Poustka A, Korf U. 2007. Infrared-based protein detection arrays for quantitative proteomics. Proteomics. 7: 558-64.

Lueking A, Huber O, Wirths C, Schulte K, Stieler KM, Blume-Peytavi U, Kowald A, Hensel-Wiegel K, Tauber R, Lehrach H, Meyer HE, Cahilla DJ. 2005. Profiling of alopecia areata autoantigens based on protein microarray technology. Mol Cell Proteomics. 4(9): 1382-90.

MacBeath G, Schreiber SL. 2000. Printing Proteins as Microarrays for High-Throughput Function Determination. Science. 289: 1760-3.

MacBeath G. 2002. Protein microarrays and proteomics. Nature Genetics Supplement. 32: 526-32.

Maciewicz RA, Knight PJ. 1988. Transmission densitometry of stained nitrocellulose paper. Analytical Biochemistry. 175(1): 85-90.

Madoz-Gúrpide J, Wang H, Misek DE, Brichory F, Hanash SM. 2001. Protein based microarrays: A tool for probing the proteome of cancer cells and tissues. Proteomics. 1279-87.

McGrath CM, Grudzien JL, Decker DA, Robbins TO. 1991. Cytometrically Coherent Transfer of Receptor Proteins on Microporous Membranes. BioTechniques. 11(3): 352-61.

McGrath CM, Grudzien JL, Levine AJ. 1995a. High Definition Cell Analysis In Situ Using Microporous Films. Cell Vision. 2(6): 499-509.

Michaud GA, Salcius M, Zhou F, Bangham R, Bonin J, Guo H, Snyder M, Predki PF, Schweitzer BI. 2003. Analyzing antibody specificity with whole proteome microarrays. Nature Biotechnology. 21(12): 1509-12.

Mircean C, Shmulevich I, Cogdell D, Choi W, Jia Y, Tabus I, Hamilton SR, Zhang W. 2005. Robust estimation of protein expression ratios with lysate microarray technology. Bioinformatics. 21(9): 1935-42.

Miyaji T, Hewitt SM, Liotta LA, Star RA. 2002. Frozen protein arrays: a new method for arraying and detecting recombinant and native tissue proteins. Proteomics. 2(11): 1489-93.

Mundinger GS, Espina V, Liotta LA, Petricoin EF, Calvo KR. 2006. Clinical phosphoproteomic profiling for personalized targeted medicine using reverse phase protein microarray. Targ. Oncol. 1: 151-67.

Nagaraj VJ, Eaton S, Thirstrup D, Wiktor P. 2008. Piezoelectric printing and probing of Lectin NanoProbeArrays for glycosylation analysis. Biochemical and Biophysical Research Communications. 375(4): 526-30.

Nam MJ, Madoz-Gúrpide J, Wang H, Lescure P, Schmalbach CE, Zhao R, Misek DE, Kuick R, Brenner DE, Hanash SM. 2003. Molecular profiling of the immune response in colon cancer using protein microarrays: Occurence of autoantibodies to ubiquitin C-terminal hydrolase L3. Proteomics. 3: 2108-15.

Narayan SB, Rakheja D, Pator JV, Rosenblatt K, Greene SR, Yang J, Wolf BA, Bennett MJ. 2006. Over-expression of CLN3P, the Batten disease protein, inhibits PANDER-induced apoptosis in neuroblastoma cells: further evidence that CLN3P has anti-apoptotic properties. Mol Genetics Metabol. 88: 178-83.

Nelson BP. 2009. Multiplexed antibody arrays for the discovery and validation of glycosylated protein biomarkers. Bioanalysis. 1(8): 1431-44.

Niedermeier M, Hennessy BT, Knight ZA, Henneberg M, Hu J, Kurtova AV, Wierda WG, Keating MJ, Shokat KM, Burger JA. 2009. Isoform-selective phosphoinositide 3_-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell–mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach. Lymphoid Neoplasia. 113(22): 5549-57.

Nishizuka S, Charboneau L, Young L, Major S, Reinold WC, Waltham M, Kouros-Mehr H, Bussey KJ, Lee JK, Espina V, Munson PJ, Petricoin EF, Liotta LA, Weinstein JN. 2003a. Proteomic profiling of NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays. PNAS. 100(24): 14229-34.

Nishizuka S, Cheng S-T, Gwadry FG, Alexander J, Major SM, Scherf U, Reinhold WC, Waltham M, Charboneau L,Young L, Bussey KJ, Kim S, Lababidi S, Lee JK, Pittaluga S, Scudiero Da, Sausville EA, Munson PJ, Petricoin EF, Liotta LA, Hewitt SM, Raffeld M, Weinstein JN. 2003b. Diagnostic markers that distinguish colon and ovarian adenocarcinomas: identification by genomic, proteomic, and tissue array profiling. Cancer Research. 63: 5243-50.

Nishizuka S, Washburn NR, Munson PJ. 2006. Evaluation method of ordinary flatbed scanners for quantitative density analysis. BioTechniques. 40(4): 442-7.

Nishizuka S, Ramalingam S, Spurrier B, Washburn FL, Krishna R, Honkanen P, Young L, Shimura T, Steeg PS, Austin J. 2008. Quantitative protein network monitoring in response to DNA damage. American Chemical Society. 7: 803-8.

Noh G, Ahn H-S, Cho N-Y, Lee S, Oh J-W. 2007. The Clinical Signifigance of Food Specific IgE/IgG4 in Food Specific Atopic Dermatitis. Pediatric Allergy and Immunology. 18: 63-70.

Nowak JE, Chatterjee M, Mohapatra S, Dryden SC, Tainsky MA. 2006. Direct production and purification of T7 pahge display proteins selected and analyzed on microarrays. BioTechniques. 40(2): 220-7.

Oehmig A, Klotzbücher A, Thomas M, Weise F, Hagner U, Brundiers R, Waldherr D, Lingnau A, Knappik A, Kubbutat MHG, Joos TO, Volkmer H. 2008. A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries. BMC Genomics. 9(441).

Oh SJ, Hong BJ, Choi KY, Park JW. 2006. Surface Modification for DNA and Protein Microarrays. OMICS A Journal of Integrative Biology. 10(3): 327-43.

Paweletz CP, Charboneau L, Bichsel VE, Simone NL, Chen T, Gillespie JW, Emmert-Buck MR, Roth MJ, Petricoin EF, Liotta LA. 2001. Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front. Oncogene. 20:1981-9.

Park S, Lee M-r, Pyo S-J, Shin I. 2003. Carbohydrate Chips for Studying High-Throughput Carbohydrate-Protein Interactions. J. Am. Chem. Soc. 126(15): 4812-9.

Park M-Y, Choi S-C, Lee HS, Kim D, Baek KE, Kim JT, Lim J-S, Yeom YI, Chung JW, Kim JW, Myung P-K, Lee HG, Kim JW, Song EY. 2008. A quantitative analysis of N-myc downstream regulated gene 2 (NDRG 2) in human tissues and cell lysates by reverse-phase protein microarray. Clinica Chimica Acta. 387: 84-9.

Pernas FG, Allen CT, Winters ME, Yan B, Friedman J, Dabir B, Saigal K, Mundinger GS, Xu X, Morris JC, Calvo KR, Van Waes C, Chen Z. 2009. Proteomic Signatures of Epidermal Growth Factor Receptor and Survival Signal Pathways Correspond to Gefitinib Sensitivity in Head and Neck Cancer. Clin. Cancer Res. 15(7): 2361-72.

Petricoin EF, Espina V, Araujo RP, Midura B, Yeung C, Wan X, Eichler GS, Johann DJ, Qualman S, Tsokos M, Krishnan K, Helman LJ, Liotta LA. 2007. Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation Is negatively associated with childhood rhabdomyosarcoma survival. Cancer Res. 67(7): 3431-40.

Poetz O, Schwenk JA, Kramer S, Stoll D, Templin MF, Joos TO. 2005. Protein microarrays: catching the proteome. Mechanisms of Ageing and Development. 126: 161-70.

Posadas EM, Simpkins F, Liotta LA, MacDonald C, Kohn EC. 2005. Proteomic analysis for the early detection and rational treatment of cancer—realistic hope? Annals of Oncology. 6: 16-22.

Ptacek J, Snyder M. 2007. 14 Yeast Protein Microarrays. Methods in Microbiology. 36: 303-29.

Qiu J, Madoz-Gúrpide J, Misek D, Kuick R, Brenner DE, Michailidis G, Haab BB, Omenn GS, Hanash S. 2004. Development of natural protein microarrays for diagnosing cancer based on and antibody response to tumor antigens. Journal of Proteome Research. 3(2): 261-7.

Predki PF. 2004. Functional protein microarrays: ripe for discovery. Current Opinion in Chemical Biology. 8: 8-13.

Ramalingam S, Honkanen P, Young L, Shimura T, Austin J, Steeg PS, Nishizuka S. 2007. Quantitative Assessment of the p53-Mdm2 Feedback Loop Using Protein Lysate Microarrays. Cancer Res. 67(13): 6247-52.

Ramaswamy A, Lin E, Chen I, Mitra R, Morrisett J, Coombes K, Ju Z, Kapoor M. 2005. Application of Protein Lysate Microarrays to Molecular Marker Verification and Quantification. Proteome Science. 3(9).

Rapkiewicz A, Espina V, Zujewski JA, Lebowitz PF, Filie A, Wulfkuhle J, Camphausen K, Petricoin EF, Liotta LA, Abati A. 2007. The needle in the haystack: application of breast fine-needle aspirate samples to quantitative protein microarray technology. Cancer. 111: 173-84.

Ratner DM, Adams EW, Su J, O’Keefe BR, Mrksich M, Seeberger PH. 2004. Probing Protein - Carbohydrate Interactions with Microarrays of Synthetic Oligosaccharides. ChemBioChem. 5: 379-83.

Renault NK, Mirotti L, Alcocer MJC. 2007. Biotechnologies in new high-throughput food allergy tests: why we need them. Biotechnol. Lett. 29: 333-9.

Repka V. 2006. Early defence response induced by two distinct elicitors derived from a Botrytis cinerea in grapevine leaves and cell suspensions. Biol. Plantarum 50: 94-106.

Robinson WH, Steinman L, Utz PJ. 2002. Proteomics Technologies for the Study of Autoimmune Disease. Arthritis & Rheumatism. 46(4): 885-93.

Rossi MA, Mash DC, deToledo-Morrell L. 2005. Spatial memory in aged rats is related to PKCƔ-dependent G-protein coupling of the MI receptor. Neurobiology of Ageing. 26: 53-68.

Rudelius M, Pittaluga S, Nishizuka S, Pham TH-T, Fend F, Jaffe ES, Quintanilla-Martinez L, Raffeld M. 2006. Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma. Blood. 108(5): 1668-76.

Sahin Ö, Fröhlich H, Löbke C, Korf U, Burmester S, Majety M, Mattern J, Schupp I, Chaouiya C, Thieffry D, Poustka A, Wiemann S, Beissbarth T, Arlt D. 2009. Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance. BMC Systems Biology. 3(1).

Sakanyan V. 2005. High-throughput and multiplex protein array technology: protein-DNA and protein-protein interactions. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 815(1-2): 77-95.

Sanchez-Carbayo M, Socci ND, Lozano JJ, Haab BB, Cordon-Cardo C. 2006. Profiling bladder cancer using targeted antibody arrays. Am. J. Pathology. 168(1): 93-103.

Scorilas A, Bjartell A, Lilja H, Moller C, Diamandis EP. 2000. Strepavidin-polyvinylamine conjugates labeled with a europium chelate: applications in immunoassay, immunohistochemistry, and microarrays. Clinical Chemistry 46: 1450-5.

Schweitzer B, Predki P, Snyder M. 2003. Microarrays to characterize protein interactions on a whole-proteome scale. Proteomics. 3: 2190-9.

Seitz H, Hutschenreiter S, Hultschig C, Zeilinger C, Zimmermann B, Kleinjung F, Schuchhardt J, Eickhoff H, Herberg FW. 2006. Differential binding studies applying functional protein microarrays and surface Plasmon resonance. Proteomics. 6: 5132-9.

Shankavaram UT, Reinhold WC, Nishizuka S, Major S, Morita D, Chary KK, Reimers MA, Scherf U, Khan A, Dolginow D, Cossman J, Kaldjian EP, Scudiero DA, Petricoin EF, Liotta LA, Lee JK, Weinstein JN. 2007. Transcript and protein expression profiles of the NCI-60 cancer cell panel: an integromic microarray study. Mol. Cancer Ther. 6(3): 820-32.

Sheehan KM, Calvert VS, Kay EW, Lu Y, Fishman D, Espina V, Aquina J, Speer R, Araujo R, Mills GB, Liotta LA, Petricoin EF, Wulfkuhle JD. 2005. Use of reverse phase protein microarrays and reference standard development for molecular network analysis of metastatic ovarian carcinoma. Mollecular and Cellular Proteomics. 4(4): 346-55.

Spurrier B, Ramalingam S, Nishizuka S. 2008. Reverse-phase protein lysate microarrays for cell signaling analysis. Nature Protocols. 3: 1796-808.

Stadtherr K, Wolf H, Lindner P. 2005. An Aptamer-Based Protein Biochip. Anal. Chem. 77:3437-43.

Sobek J, Bartscherer K, Jacob A, Hoheisel JD, Angenendt P. 2006. Microarray Technology as a Universal Tool for High-Throughput Analysis of Biological Systems. Combinatorial Chemistry & High Throughput Screening. 9: 365-80.

Stears RL, Martinsky T, Schena M. 2003. Trends in microarray analysis. Nature Medicine. 9(1): 140-5.

Steller S, Angenendt P, Cahill DJ, Heuberger S, Lehrach H, Kreutzberger J. 2005. Bacterial protein microarrays for identification of new potential diagnostic markers for Neisseria meningitidis infections. Proteomics. 5(8): 2048-55.

Stevens EV, Nishizuka S, Antony S, Reimers M, Varma S, Young L, Munson PJ, Weinstein JN, Kohn EC, Pommier Y. 2008. Predicting cisplatin and trabectedin drug sensitivity in ovarian and colon cancers. Mol. Cancer Ther. 7(1): 10-18.

Stillman BA, Tonkinson JL. 2000. FAST slides: A novel surface for microarrays. BioTechniques. 29(3): 630-5.

Sundaresh S, Randall A, Unal B, Petersen JM, Belisle JT, Hartley MG, Duffield M, Titball RW, Davies DH, Felgner PL, Baldi P. 2007. From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis. Bioinformatics. 23(13): i508-18.

Tang N, Tornatore P, Weinberger SR. 2003. Current Developments in SELDI Affinity Technology. Mass Spectrometry Reviews. 23: 34-44.

Tannapfel A, Anhalt K, Häusermann P, Sommerer F, Benicke M, Uhlmann D, Witzigmann H, Hauss J, Wittekind C. 2003. Identification of novel proteins associated with hepatocellular carcinomas using protein microarrays. J. of Pathology. 2003:238-49.

Tibes R, Qiu YH, Lu Y, Hennessy B, Andreeff M, Mills GB, Kornblau SM. 2006. Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells. Mol. Cancer Ther. 5(10): 2512-21.

Tomizaki Ki-y, Usui K, Mihara H. 2005. Protein-Detecting Microarrays: Current Accomplishments and Requirements. ChemBioChem. 6: 782-99.

Tsavachidou-Fenner D, Tannir N, Tamboli P, Liu W, Petillo D, The B, Mills GB, Jonasch E. 2010. Gene and protein expression markers of response to combined antiangiogenic and epidermal growth factor targeted therapy in renal cell carcinoma. Ann. Oncol.

Uttamchandani M, Yao SQ. 2008. Peptide Microarrays: Next Generation Biochips for Detection, Diagnostics and High-Throughput Screening. Current Phamaceutical Design.

VanMeter AJ, Rodriguez AS, Bowman ED, Jen J, Harris CC, Deng J, Calvert VS, Silvestri A, Fredolini C, Chandhoke V, Petricoin EF, Liotta LA, Espina V. 2008. Laser Capture Microdissection and Protein Microarray Analysis of Human Non-small Cell Lung Cancer. Molecular and Cellular Proteomics. 7(10): 1902-24.

Van Herpen TWJM, Riley M, Sparks C, Jones HD, Gritsch C, Dekking EH, Hamer RJ, Bosch D, Salentijn, Smulders MJM, Shewry PR, Glissen JWJ. 2008. Detailed Analysis of the Expression of an Alpha-gliadin Promoter and the Deposition of Alpha-gliadin Protein During Wheat Grain Development. Annals of Botany. 102: 331-42.

Van Oss CJ, Good RJ, Chaudhury MK. 1987. Mechanism of DNA (Southern) and protein (Western) blotting on cellulose nitrate and other membranes. J. Chromatogr. 391(1): 53-65.

Wang CC, Huang R-P, Sommer M, Lisoukov H, Huang R, Lin Y, Miller T, Burke J. 2002. Array-Based Multiplexed Screening and Quantitation of Human Cytokines and Chemokines. The Journal of Proteome Research. 1: 337-43.

Wang D, Liu S, Trummer BJ, Deng C, Wang A. 2002. Carbohydrate microarrays for the recognition of cross-reactive molecular markers of microbes and host cells. Nature Biotechnology. 20: 275-81.

Wang D. 2003. Carbohydrate Microarrays. Proteomics. 3: 2167-75.

Wang X, Liu L-H, Ramstrӧm O, Yan M. 2009. Engineering Nanomaterial Surfaces for Biomedical Applications. Exp. Biol. Med. 234:1128-39.

Wang X, Ramström O, Yan M. 2010. Glyconanomaterials: Synthesis, Characterization, and Ligand Presentation. Adv. Mater. 22: 1946-53.

Wei Q, Wang L-E, Sturgis EM, Mao L. 2005. Expression of nucleotide excision repair proteins in lymphocytes as marker of susceptibility to squamous cell carcinomas of the head and neck. Cancer Epidemiol. Biomarkers Prev. 14(8): 1961-6.

Wiley PR, Tosi P, Evrard A, Lovegrove A, Jones HD, Shewry PR. 2007. Promoter analysis and immunolocalisation show that puroindoline genes are exclusively expressed in starchy endosperm cells of wheat grain. Plant Mol. Bio. 64: 125-36.

Wingren C, Steinhauer C, Ingvarsson J, Persson E, Larsson K, Borrebaeck CAK. 2005. Microarrays based on affinity-tagged single-chain Fv antibodies: Sensitive detection of analyte in complex proteomes. Proteomics. 5: 1281-91.

Wu P, Castner DG, Grainger DW. 2008. Diagnostic devices as biomaterials: a review of nucleic acid and protein microarray surface performance issues. J. Biomater. Sci. Polymer Edn. 19(6): 725-53.

Wulfkuhle JD, Aquino JA, Calvert VS, Fishman DA, Coukos G, Liotta LA, Petricoin EF. 2003. Signal pathway profiling of ovarian cancer from human tissue specimen using reverse-phase protein microarrays. Proteomics. 3: 2085-90.

Wulfkuhle JD, Edmiston KH, Liotta LA, Petricoin EF. 2006. Technology Insight: pharmacoproteomics for cancer-promises of patient-tailored medicine using protein microarrays. Nature Clinical Practice. 3(5): 256-68.

Yamamoto, Clark JD, Pastor JV, Gurnani P, Nandi A, Kurosu H, Miyoshi M, Ogawa Y, Castrillon DH, Rosenblatt KP, Kuro-o M. 2005. Regulation of oxidative stress by the anti-aging hormone Klotho. J. Biol. Chem. 280(45): 38029-34.

Yan F, Sreekumar A, Laxman B, Chinnaiyan AM, Lubman DM, Barder TJ. 2003. Protein microarrays using liquid phase fractionation of cell lysates. Proteomics. 3: 1228-35.

Yang F, YuXin G, Yan Z, Juan C, Mian L. 2009. A microfluidic-based system to quantify cell capture efficiency. Sci. China Ser. C-Life Sci. 52(2): 173-81.

Yeretssian G, Lecocq M, Lebon G, Hurst HC, Sakanyan V. 2005. Competition on Nitrocellulose-immobilized Antibody Arrays. Molecular & Cellular Proteomics. 4: 605-17.

Zha H, Raffeld M, Charboneau L, Pittaluga S, Kwak LW, Petricoin EF, Liotta LA, Jaffe ES. 2004. Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray. Laboratory Investigation. 84: 235-44.

Zhong L, Hidalgo GE, Stromberg AJ, Khattar NH, Jett JR, Hirschowitz EA. 2005. Using protein microarray as a diagnostic assay non-small cell lung cancer. Am. J. Resp. Crit. Care Med. 172: 1308-14.

Zhou X, Zhou J. 2006. Oligosaccharide microarrays fabricated on aminooxyacetyl functionalized glass surface for characterization of carbohydrate-protein interaction. Biosensors and Bioelectronics. 21(8): 1451-58.

Zhao J, Patwa TH, Qiu W, Shedden K, Hinderer R, Misek DE, Anderson MA, Simeone DM, Lubman DM. 2007. Glycoprotein Microarrays with Multi-Lectin Detection: Unique Lectin Binding Patterns as a Tool for Classifying Normal, Chronic Pancreatitis and Pancreatic Cancer Sera. Journal of Proteomoe Research. 6: 1864-74.

Zhu H, Bilgin M, Bangham R, Hall D, Casamayor A, Bertone P, Lan N, Jansen R, Bidlingmaier S, Houfek T, Mitchell T, Miller P, Dean RA, Gerstein M, Snyder M. 2001. Global Analysis of Protein Activities Using Proteome Chips. Science. 293: 2101-5.

Zhu H, Snyder M. 2003. Protein chip technology. Current Opinion in Chemical Biology. 7: 55-63.

Zhu H, Hu S, Jona G, Zhu X, Kreiswirth N, Willey BM, Mazzulli T, Liu G, Song Q, Chen P, Cameron M, Tyler A, Wang J, Wen J, Chen W, Compton S, Snyder M. 2006. Severe acute respiratory syndrome diagnostics using a coronavirus protein array. PNAS. 103(11): 4011-6.


Browna DW, Gunningb KB, Henrya DM, Awdehc ZL, Brinkera JP, Tziporia S, Herrmanna JE. 2008. A DNA Oligonucleotide Microarray for Detecting Human Astrovirus Serotypes. J. Virol. Methods. 147(1): 86-92.

Gildersleeve JC, Oyelaran O, Simpson JT, Allred B. 2008. Improved Procedure for Direct Coupling of Carbohydrates to Proteins via Reductive Amination. Bioconjug. Chem. 19(7): 1485-90.

Poetz O, Ostendorp R, Brocks B, Schwenk JM, Stoll D, Joos TO, Templin MF. 2005. Protein microarrays for antibody profiling: Specificity and affinity determination on a chip. Proteomics.

Sevecka M, MacBeath G. 2006. State-based discovery: Multidimensional screen smallmolecule modulators of EGF signaling. Nat. Methds. 3(10): 825-31.

Rondini S, Pingle MR, Das S, Tesh R, Rundell MS, Hom J, Stramer S, Turner K, Rossmann SN, Lanciotti R, Spier EG, Munoz-Jordan J, Larone D, Spitzer E, Barany F, Golightly LM. 2008. Development of Multiplex PCR-Ligase Detection Reaction Assay for Detection of West Nile Virus. Journal of Clinical Microbiology. 2269-79.

FlexWell™ Incubation Chambers:

Li N, Wang Y, Pothukuchy A, Syrett A, Husain N, Gopalakrisha S, Kosaraju P, Ellington AD. 2008. Aptamers that recognize drug-resistant HIV-1 reverse transcriptase. Nucleic Acids Research. 36(21): 6739-51.

Online Ordering

Nitrocellulose-Coated Film Substrates, ProPlate™ and FlexWell™ Incubation Chambers are available online from the EMS Catalog. For ordering or product information, click on the product name -