Questions? 800-523-5874 | [email protected]
- TEM Grids
- Prepmaster™ Specimen Preparation Robot
- TEM Window Grids
- Omniprobe Nanomanipulation Systems
- K-kit Wet "Liquid" TEM Kit
- Specimen Mounts
- SEM Specimen Holders
- Index and Finder SEM Grids
- SEM for Forensics
- SEM Sample Preparation Station Materials
- Cryogenic Personal Protection Equipment
- Cryo Dewars & Flasks
- Cryogenic Grids & Accessories
- Cryogenic Vials & Racks
- Cooling Chambers & Ice Baths
- Prepmaster™ Specimen Preparation Robot
- Laboratory Microwave Ovens
- LYNX II Automated Tissue Processor
- EMS Poly III
- Microtomes
- Tissue Slicers
- Rapid Immersion Freezer
- Heaters & Chillers
- SEM Cooling Stage
- Glow Discharge Systems
- Sputter Coaters & Carbon Coaters
- Stages
- Freeze Dryers
- Critical Point Dryers
- Cryo-SEM Preparation System
- Specimen Transfer Systems
- Decontaminators
- Desiccators
- Centrifuges
- Dry Baths
- Stirrers, Hot Plates
- Vortexers & Magnetic Mixers
- Rotators & Rockers
- Ovens & Incubators
- Vibration Isolation
- Air Sampling
- Vacuum Pumps
EMS Technical Tips
Why Ultra Small Gold Conjugates
Ultra Small Particle Size
- more gold particles per secondary antibody instead of more antibodies per gold particle
- reduced steric hinderance
- more gold particles per surface area in the specimen
Reduced Molecular Weight
- increased diffusion rates
- ultra small probes behave similar as uncoupled antibodies
Reduced Probe Size
- reduced overall probe size
- reduced hydrodynamic radius (less rigid water coat of water dipoles surrounding negatively charged gold particle)
- significantly increased penetration into sections and tissues
The Choice for Ligand-Receptor Interactions
- each ligand is separate
- no capping or patching, each probe unit consists of a single ligand
Universal Probes
- optimally suited for high resolution EM
- optimally suited for standard immunoelectron microscopy
- optimally suited for immunohistochemistry at the LM level
- optimally suited for bio-assays
One Probe for All Purposes
- direct comparability of results and approaches
- probes can be used for labeling at the LM and EM level