The size of Ultra Small gold and 2nm gold nanoparticles can be increased by silver enhancement allowing their visualization at electron and light microscopy levels. This process involves the gold particle mediated reduction of silver ions and deposition of metallic silver on the particle surface.

Aurion provides two types of silver enhancement reagents, R-Gent SE-EM and R-Gent SE-Intense, the successor of R-Gent SE-LM with improved signal contrast, reaction speed and reproducibility.

AURION R-Gent SE-EM is a high efficiency silver enhancement reagent for electron microscopy applications. It is characterized by its homogeneous enhancement, light insensitivity, low viscosity, near neutral pH and virtually no autonucleation.

Aurion R-Gent SE-Intense, can be used for light microscopy and blotting applications. It produces a brown to black enhancement when viewed by bright field light microscopy. Furthermore, it is light insensitive, has near neutral pH and extremely low autonucleation.

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