EMS Decalcifier with HCl/EDTA combines acid and chelating decalcifying agents, plus a tartrate buffer for prevention of cellular swelling and distortion. This solution provides rapid decalcification, maintains excellent cellular morphology, and is suitable for all bone specimens from bone marrow biopsies and disc material (light bone) to femoral head and long bone sections (compact bone). It is not recommended for use when proteoglycan preservation in articular cartilage is important.