Ideal Substrate for Cryo-Microscopy
"Our initial findings indicate that viral particles prepared on Cryo-SiN, exhibited greater contrast in comparison to those prepared on holey carbon films under the same conditions. As a result, we were able to calculate 3D reconstructions of viral particles prepared on Cryo-SiN using a fraction of the images required for samples prepared on holey carbon films." Tanner et al. Microscopy & Microanalysis Abstract, 2013
- Avoid substrate degradation seen with carbon grids
- Plasma cleanable to reduce contaminants
- Our proprietary carbon coating may also improve charge dissipation leading to a reduction in beam induced movement
- Large 500 µm windows provide ~50 x 50 µm viewing from any orientation at 70 degrees of tilt for tomography