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Retriever for Antigen Unmasking

A reliable, time tested solution to unmask antigen on formalin-fixed sections

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Retriever for Formalin-fixed, Paraffin Embedded TissuesOur Unique Retriever solves the problem of staining formalin fixed tissues. This is an affordable solution to all known major problems with immunohistochemistry on paraffin sections. Ease of use combined with high reproducibility of the results will give you the best quality immunostaining.

The Retriever is a bench-top model for thermally processing slides of formalin-fixed, paraffin embedded tissues prior to immunostaining. The model has been designed to ensure identical processing of all the samples during a processing cycle, as well as the identical processing of the samples in individual sessions. The retriever preserves processed tissues.

Now you can:

  • Run antigen unmasking in 6 various buffers at once
  • Perform gentle antigen retrieval that does not damage the tissue morphology
  • Get identical results every time
  • Compare series of slides treated in independent sessions

How does the Retriever work?

The Retriever is essentially a pressure cooker specifically designed to unmask the antigen on tissue sections. The core principle is heating of the chambers with the slides at a high temperature (>120°C) and a high pressure. Sensors control the heating profile for the temperature and pressure to be reached at certain pace and over certain time. We did a lot of tests to find the optimal settings.

When the required temperature is reached, it will be kept for several minutes. After that, the slides will be cooling over 2 hours. Specially designed thermal walls of the unit control the speed of cooling of the inner chamber and slides.

Step3Who would benefit from using our Retriever?

  • Investigative Pathology, where the high quality of staining (a picture may be published!) is required.
  • Any labs that is short on technical personnel: any student or post-doc can process slides for the staining without using much time
  • Small routine pathology labs, where a limited number of slides should be processed daily
  • Anyone who uses highly valuable samples, such as tissue arrays or unique tissue samples: Simplicity and reliability of the unit ensures the safety of your sample, and a high quality antigen unmasking

How To Use:

Step1 Step2Step 1.

Deparaffinized sections on slides are placed into the Processing (Tissue Slide) Chambers. Retriever can accommodate simultaneously from 1 to 6 Chambers, which allows you to process a series of slides in up to 6 different antigen unmasking buffers within the same session. Fill the chambers with a buffer of your choice.

Step4 Step5Step 2.

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Antigen Retriever

Bench-top model for thermally processing slides of formalin-fixed, paraffin embedded tissues prior to immunostaining. Ensures identical processing of all samples during a processing cycle and preserves processed tissues.
Cat # Description MSDS Pack Price Quote Quantity
Cat #: 62700-20 Description: Retriever 220 Volt Pack: Each Price: $2,438.00 Add to Quote:
Cat #: 62700-10 Description: Retriever 115 Volt Pack: Each Price: $2,438.00 Add to Quote:
Cat #: 62706-10 Description: R-Buffer A (10X) Pack: 250 mL Price: $77.50 Add to Quote:
Cat #: 62706-11 Description: R-Buffer B (10X) Pack: 250 mL Price: $77.50 Add to Quote:
Cat #: 62706-12 Description: R-Buffer C (10X) Pack: 250 mL Price: $77.50 Add to Quote:
Cat #: 62706-13 Description: R-Buffer U (10X) Pack: 250 mL Price: $77.50 Add to Quote:
Cat #: 62707-10 Description: R-Buffer Ag (2X) Pack: 250 mL Price: $77.50 Add to Quote:
Cat #: 62707-11 Description: R-Buffer Bg (2X) Pack: 250 mL Price: $77.50 Add to Quote:
Cat #: 62707-12 Description: R-Buffer Cg (2X) Pack: 250 mL Price: $77.50 Add to Quote:
Cat #: 62707-13 Description: R-Buffer Ug (2X) Pack: 250 mL Price: $77.50 Add to Quote:
Cat #: 62705-01 Description: Slide Chamber Pack: 3 Pack Price: $196.00 Add to Quote:
Cat #: 62705-02 Description: Chamber Rack Pack: Each Price: $114.50 Add to Quote:
Cat #: 62705-03 Description: Lifting Device Pack: Each Price: $30.50 Add to Quote:
Cat #: 62705-04 Description: Cord Set (Uk) Pack: Each Price: $77.50 Add to Quote:
Cat #: 62705-05 Description: Cord Set (Europe) Pack: Each Price: $77.50 Add to Quote:
Cat #: 62705-06 Description: Cord Set (Us) Pack: Each Price: $77.50 Add to Quote:
Cat #: 62705-07 Description: Green Silicone Sealing Gasket Pack: Each Price: $93.50 Add to Quote:

R-UNIVERSAL Epitope Recovery Buffer (10x stock)

The EMS Universal Buffer may be used in any heat-induced epitope recovery system. In the Antigen Retriever (62700 Series), it guarantees the highest rate of success in recovering epitope for any antibody.
Cat # Description MSDS Pack Price Quote Quantity
Cat #: 62719-10 Description: R-Universal Epitope Recovery Buffer (10x stock) Pack: 125 mL Price: $178.00 Add to Quote:
Cat #: 62719-20 Description: R-Universal Epitope Recovery Buffer (10x stock) Pack: 500 mL Price: $280.00 Add to Quote:
Cat #: 62719-30 Description: T-Universal Epitope Recovery Buffer 10x Stock Pack: 125 mL Price: $90.00 Add to Quote:
Cat #: 62719-35 Description: T-Universal Epitope Recovery Buffer 10x Stock Pack: 500 mL Price: $127.00 Add to Quote:
Cat #: 62719-40 Description: U-Universal Epitope Recovery Buffer 10x Stock Pack: 125 mL Price: $116.50 Add to Quote:
Cat #: 62719-45 Description: U-Universal Epitope Recovery Buffer 10x Stock Pack: 500 mL Price: $132.50 Add to Quote:
Cat #: 62719-50 Description: L-Universal Epitope Recovery Buffer 10x Stock Pack: 125 mL Price: $88.00 Add to Quote:
Cat #: 62719-55 Description: L-Universal Epitope Recovery Buffer 10x Stock Pack: 500 mL Price: $144.00 Add to Quote:
Cat #: 62719-60 Description: H-Universal Epitope Recovery Buffer 10x Stock Pack: 125 mL Price: $88.00 Add to Quote:
Cat #: 62719-65 Description: H-Universal Epitope Recovery Buffer 10x Stock Pack: 500 mL Price: $144.00 Add to Quote:
Cat #: 62719-70 Description: Epitope Recovery Set Pack: Set Price: $456.00 Add to Quote:

ImmunoSaver Antigen Retriever

For Immunostaining with quick and easy activation of cell membranes and nucleus. Immunosaver provides efficient antigen retrieval for successful immunostaining of a wide variety of antigens under optimized conditions.
Cat # Description MSDS Pack Price Quote Quantity
Cat #: 64142 Description: Immunosaver Antigen Retriever Pack: 100 mL Price: $265.00 Add to Quote:

Retriever Tissue Slides

High adhesive glass microscope slides for paraffin-embedded tissue section, including tissue arrays are designed and optimized for the Antigen Retriever to preserve the section attachment and tissue morphology during heat-induced epitope recovery.
Cat # Description Pack Price Quote Quantity
Cat #: 71880-50 Description: Retriever Tissue Slides, HistoBond + F, Blue Pack: 100 Pack Price: $105.00 Add to Quote:
Cat #: 71880-50-CS Description: Retriever Tissue Slides, HistoBond + F, Blue Pack: 20 Case Price: $1,574.00 Add to Quote:
Cat #: 71890-50 Description: Retriever Tissue Slides, HistoBond + R, Orange Pack: 100 Pack Price: $73.00 Add to Quote:
Cat #: 71890-50-CS Description: Retriever Tissue Slides, HistoBond + R, Orange Pack: 20 x 100 pack Price: $1,237.00 Add to Quote:
Cat #: 71890-51 Description: Retriever Tissue Slides, HistoBond + X, White Pack: 100 Pack Price: $78.50 Add to Quote:
Cat #: 71890-51-CS Description: Retriever Tissue Slides, HistoBond + X, White Pack: 20 x 100 pack Price: $1,317.50 Add to Quote: